{"id":1674,"date":"2013-08-20T20:09:26","date_gmt":"2013-08-20T20:09:26","guid":{"rendered":"http:\/\/www.ciencianews.com.br\/homologacao\/?page_id=1674"},"modified":"2013-08-23T13:13:42","modified_gmt":"2013-08-23T13:13:42","slug":"atlas-hematologico-mieloma-multiplo","status":"publish","type":"page","link":"https:\/\/www.ciencianews.com.br\/index.php\/ciencia\/atlas-hematologico\/atlas-hematologico-mieloma-multiplo\/","title":{"rendered":"Atlas Hematol\u00f3gico \u2013 Mieloma M\u00faltiplo"},"content":{"rendered":"<div id=\"amw_galleria_slideshow_1\" class=\"amw-galleria-slideshow\"><\/div>\n<script type=\"text\/javascript\">jQuery(document).ready(function(){ jQuery(\"#amw_galleria_slideshow_1\").galleria({\"dataSource\":[{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm01.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm01.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm01-150x150.jpg\",\"title\":\"\",\"description\":\"O Mieloma M\\u00faltiplo \\u00e9 uma doen\\u00e7a insidiosa que inicia com a prolifera\\u00e7\\u00e3o de plasm\\u00f3citos na medula \\u00f3ssea. A ocupa\\u00e7\\u00e3o de espa\\u00e7os na medula torna os ossos fr\\u00e1geis, quebradi\\u00e7os e formam tumores medulares &#8211; o mieloma.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm02.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm02.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm02-150x150.jpg\",\"title\":\"\",\"description\":\"As m\\u00faltiplas les\\u00f5es tumorais, da\\u00ed a designa\\u00e7\\u00e3o de mieloma m\\u00faltiplo, causam anemia, excessiva libera\\u00e7\\u00e3o de um s\\u00f3 tipo de imunoglobulina no plasma. A figura mostra m\\u00faltiplas les\\u00f5es no cr\\u00e2nio.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm03.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm03.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm03-150x150.jpg\",\"title\":\"\",\"description\":\"Com o passar dos meses, a medula \\u00f3ssea se torna totalmente ocupada por plasm\\u00f3citos, aus\\u00eancia de leuc\\u00f3citos granul\\u00f3citos e de precursores eritrocit\\u00e1rios e plaquet\\u00e1rios\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm04.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm04.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm04-150x150.jpg\",\"title\":\"\",\"description\":\"No sangue perif\\u00e9rico \\u00e9 poss\\u00edvel observar eritr\\u00f3citos em forma de empilhamento (roleaux) e, as vezes, alguns plasm\\u00f3citos.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm05.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm05.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm05-150x150.jpg\",\"title\":\"\",\"description\":\"Em alguns pacientes com mieloma m\\u00faltiplo, a concentra\\u00e7\\u00e3o muito elevada de imunoglobulina anormal pode induzir a crioglobulinemia com precipita\\u00e7\\u00e3o no tubo com o soro do paciente e gerar agregados de imunoglobulinas no esfrega\\u00e7o.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm06.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm06.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm06-150x150.jpg\",\"title\":\"\",\"description\":\"Quando h\\u00e1 muita forma\\u00e7\\u00e3o de crioglobulina, \\u00e9 poss\\u00edvel observar na medula \\u00f3ssea e no sangue perif\\u00e9rico, neutr\\u00f3filos com crioglobulinas fagocitadas, como nesta foto.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm07.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm07.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm07-150x150.jpg\",\"title\":\"\",\"description\":\"A excessiva forma\\u00e7\\u00e3o de globulinas no citoplasma de plasm\\u00f3cito forma um novo tipo de estrutura celular: a c\\u00e9lula de Mott, vis\\u00edvel em esfrega\\u00e7o de medula de paciente com mieloma m\\u00faltiplo.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm08.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm08.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm08-150x150.jpg\",\"title\":\"\",\"description\":\"H\\u00e1 casos de mieloma m\\u00faltiplo em que o paciente apresenta c\\u00e9lulas plasmocit\\u00e1rias gigantes na medula \\u00f3ssea, com muitos n\\u00facleos.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm09.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm09.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm09-150x150.jpg\",\"title\":\"\",\"description\":\"H\\u00e1 casos de mieloma m\\u00faltiplo em que os plasm\\u00f3citos medulares tem seus citoplasmas excessivamente carregados de imunoglobulinas e, ao serem corados, apresentam-se como c\\u00e9lulas flamejantes.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm10.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm10.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm10-150x150.jpg\",\"title\":\"\",\"description\":\"A imunofenotipagem das c\\u00e9lulas plasmocit\\u00e1rias do mieloma m\\u00faltiplo s\\u00e3o CD38 positivas em sangue de medula. Observar o roleaux dos eritr\\u00f3citos.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm11a.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm11a.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm11a-150x150.jpg\",\"title\":\"\",\"description\":\"A eletroforese de prote\\u00ednas s\\u00e9ricas do paciente com mieloma m\\u00faltiplo mostra excessiva concentra\\u00e7\\u00e3o de um s\\u00f3 tipo de imunoglobulina, no caso a Ig M, na regi\\u00e3o de gama-globulina.\"},{\"image\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm11b.jpg\",\"big\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm11b.jpg\",\"thumb\":\"https:\\\/\\\/www.ciencianews.com.br\\\/wp-content\\\/uploads\\\/2013\\\/08\\\/mm11b-150x150.jpg\",\"title\":\"\",\"description\":\"O tra\\u00e7ado gr\\u00e1fico da eletroforese anterior mostra o &#8220;pico monoclonal&#8221; da gama-gobulina do mieloma m\\u00faltiplo.\"}],\"width\":\"auto\",\"height\":0.76000000000000001,\"autoplay\":false,\"transition\":\"slide\",\"initialTransition\":\"fade\",\"transitionSpeed\":0,\"_delayTime\":4000,\"_hideControls\":false,\"_thumbnailMode\":\"grid\",\"_captionMode\":\"on_expand\"}); });<\/script>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":150,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","_joinchat":[],"footnotes":""},"class_list":["post-1674","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false,"business-hub-blog":false,"business-hub-work":false},"uagb_author_info":{"display_name":"real","author_link":"https:\/\/www.ciencianews.com.br\/index.php\/author\/real\/"},"uagb_comment_info":0,"uagb_excerpt":null,"_links":{"self":[{"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/pages\/1674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/comments?post=1674"}],"version-history":[{"count":3,"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/pages\/1674\/revisions"}],"predecessor-version":[{"id":1801,"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/pages\/1674\/revisions\/1801"}],"up":[{"embeddable":true,"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/pages\/150"}],"wp:attachment":[{"href":"https:\/\/www.ciencianews.com.br\/index.php\/wp-json\/wp\/v2\/media?parent=1674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}